The JS2450 is a JS series solid body electric guitar model introduced by Ibanez in mid 2014. It is a signature model of American guitarist Joe Satriani which is produced in Japan by FujiGen

The JS2450 was introduced at the 2014 Summer NAMM Show. It is very similar to the JS2410 with the only apparent difference being the finish and the JS2450's chrome pickups, rather than the color-matched pickups on the JS2410.

The JS2450 alder body bolted to a maple and bubinga neck with a 24-fret rosewood fingerboard with mother of pearl dot position markers. Components include DiMarzio pickups with color-matched bobbins with a Mo Joe humbucker at the bridge and a Satch Track single-coil sized humbucker at the neck, an original Edge double locking tremolo bridge with a carbon fiber Ultralite tremolo arm and Gotoh tuning machines.

For 2016, a new Muscle Car Black finish was added; this finish was discontinued after 2017.